The collection is arranged chronologically.

The letters from Georgia O'Keeffe to Charles Wickham "Wick" Moore relate to their personal friendship. Among the letters are three postcards with images of O'Keeffe's Abiquiu property on the front and one photograph of the Rio Chama.

The original letters from Charles Wickham Moore to Georgia O'Keeffe are located in the Alfred Stieglitz / Georgia O'Keeffe Archive, Yale Collection of American Literature at the Beinecke Rare Book and Manuscript Library.